In Chagas disease, TBX21 and IFN-γ expression are correlated with the left ventricular dilation, and the ratio between TBX21 and GATA3 expression is significantly higher in CCC than in non-inflammatory cardiomyopathy (58), which were also confirmed in our data in both control to CCC or DCM comparisons. This evidence concerns the gene TBX21 and familial dilated cardiomyopathy.