For example, lncRNA UCA1 could activate the mTOR pathway, mediate the regulation of urothelial cancer associated 1 (UCA1) to HK2 through activation of signal transducer and activator of transcription 3 (STAT3), then promote glycolysis, exert promotion effects on tumorigenesis in bladder cancer (Li et al., 2014). This evidence concerns the gene HK2 and urinary bladder cancer.