In other words, overexpression of tRF-Leu-CAG increased the activity of AURKA and thus promoted cell cycle progression at the G0/G1 phase in NSCLC, which indicated that tsRNAs like tRF-Leu-CAG could regulate cell cycle progression by modulating AURKA activity (Braicu et al., 2019). The gene discussed is AURKA; the disease is non-small cell lung carcinoma.