The development of a hypercoagulable state in COVID-19 patients is due to the widespread inflammatory processes COVID-19 causes within the vasculature, often referred to as a “cytokine storm.” This is where the virus causes the body to produce high levels of inflammatory and pro-coagulative factors, including CRP, D-dimer, IL-6, and fibrinogen. The gene discussed is CRP; the disease is COVID-19.