NEFL and Guillain-Barre syndrome: Thus, in the present study, we aimed to: (1) determine the CSF-NfL levels by enzyme-linked immunosorbent assay (ELISA) in healthy children and pediatric GBS patients; (2) analyze the value of CSF-NfL levels in early diagnosis and therapeutic efficacy in pediatric GBS; and (3) examine the association between CSF-NfL levels and clinical features as well as the outcome of Guillain-Barré syndrome in children.