The data showed that there were significant differences in the mRNA expression levels of ATP2A2, ATP6V1D, CAP2, and SYNJ1 between the AD model group and the normal HT22 cell group (P < 0.05, ATP2A2; P < 0.05, ATP6V1D; P < 0.01, CAP2; P < 0.05, SYNJ1) (Figure 9). This evidence concerns the gene CAP2 and Alzheimer disease.