Albumin (ALB), interleukin-6 (IL6), vascular endothelial growth factor A (VEGFA), epidermal growth factor (EGF), epidermal growth factor receptor (EGFR), JUN, MYC, CASP3, and MAPK1/8 are most important genes in WHQD's pharmacological effects on PCOS according to their degree. This evidence concerns the gene MAPK1 and polycystic ovary syndrome.