MCUR1 and hepatocellular carcinoma: To investigate the involvement of the circ_0000098/miR-383/MCUR1 pathway during HCC development in vivo, physiological saline (NC), DOX, DOX/sh-NC@PLT, and DOX/sh-1@PLT were administered into HCC model mice from day 14 to day 56 (Fig. 7A).