To further confirm the binding specificity of the tribody 53G for LAG-3, we investigated also its binding on HuT 78 cell line, which is derived from CD4+ human T cell lymphoma and expresses high levels of LAG-3 receptor, but low or absent levels of PD-1 and PD-L1. This evidence concerns the gene LAG3 and T-cell non-Hodgkin lymphoma.