The group of patients with asthma comprised significantly more females (P = 0.001), had lower body mass index (BMI) (P = 0.019), higher prevalence of NSAIDs hypersensitivity (P = 0.001) and allergic rhinitis (P = 0.007), higher levels of eosinophil in blood (P ≤ 0.001) and nasal secretions (P = 0.036), serum T-IgE (P < 0.001), and FeNO (P < 0.001) compared to patients without asthma (Table 1). The gene discussed is IGHE; the disease is allergic rhinitis.