In addition, three-node analysis demonstrated that both CGRP mAbs (RR:6.29, 95% CrI: 4.07 to 10.29) and CGRP receptor mAbs (RR: 5.38, 95% CrI: 2.58 to 13.21) achieved a 75% or greater reduction in the monthly number of migraine days than placebo. The gene discussed is CALCA; the disease is migraine disorder.