CALCA and migraine disorder: According to the three-node analysis (Table 2), both CGRP mAbs (MD: -3.29, 95% CrI: − 3.97 to − 2.76) and CGRP receptor mAbs (MD: -1.74, 95% CrI: − 2.72 to − 1.11) resulted in greater reduction in mean monthly migraine days than placebo.