Forty-six candidate genes are prioritized by multiple approaches (42 for LST and 6 for MVPA; 2 overlap) and point to endocytosis (CNIH2, RAB1B, KLC2, PACS1, REPS1, DNM3, EXOC4), locomotion (CADM2, KLC2) and myopathy (MLF2, HERC1, KLC2, SIL1) as relevant pathways (Supplementary Tables 25 and 26, and Supplementary Note). The gene discussed is CADM2; the disease is myopathy.