Although only one miRNA we identified was also detected as differentially expressed among AD patients in the Nie et al. study (hsa-let-7b-5p), as we demonstrated in the results of our linear regression and linear mixed models, their cross-sectional study also reported that the KEGG pathways of the miRNAs they found differentially regulated in AD patients included fatty acid biosynthesis, Hippo signaling, ECM-receptor interactions, and TGF-β signaling. Here, TGFB1 is linked to Alzheimer disease.