SH2D3A and infection: To determine whether the effect of anti-E2 antibody on nsP1 DVG production is host cell type specific and potentially related to its antiviral effects, BHK-21, cAP-7, and dAP-7 cells were infected with SINV (MOI of 10) and treated with anti-E2 antibody or media (untreated) at 4 h after infection.