NR4A2 and autoimmune disease: This expansion of Foxp3−PD‐1+GITRhi Th cells was NR4A2 dependent and appeared to be associated with the development of self‐reactive responses as few PD‐1+GITRhi were observed among conventional non‐Treg Th cells in Nr4a2 cKO littermates (Fig EV3B), or in mice on a background that do not develop spontaneous autoimmune disease (Fig EV3C and D).