To ensure that both the MMR-proficient (pMMR) and induced dMMR (idMMR) neuroblastoma cells had similar baseline growth kinetics, we conducted an Incucyte cell proliferation assay with multiple clones and found no significant differences in cell growth rates between the idMMR and the WT parental pMMR neuroblastoma cells (Figure S4M). The gene discussed is MRC1; the disease is neuroblastoma.