Furthermore, T cells in idMMR tumors did not exhibit increased expression of single or multiple inhibitory receptors, including PD1, LAG3, TIM3, and TIGIT, which indicates that inducing MMR deficiency in neuroblastoma tumors and the potential exposure to more antigens does not induce exhaustion in these T cells (Figures 2J, 2K, and S5F). This evidence concerns the gene LAG3 and neuroblastoma.