NOD1 and colorectal carcinoma: Given the role of NOD1 in the recognition of peptidoglycans (DAP) or effector proteins (SipA, SopE) present on pathogens (Keestra‐Gounder & Tsolis, 2017), liquid chromatography‐mass spectrometry (LC‐MS) was employed to analyse the protein cargo isolated from human CRC‐EVs (EV‐HT29) and the control (human normal colon cell line CCD18Co derived EVs, EV‐CCD18Co) (Figure S5a).