IL6 and cancer: We analyzed the expression of proinflammatory cytokines (IL‐6) and chemokines (C‐C motif chemokine ligand 1(CCL1) and CCL2) that are known to contribute to cancer cell metastasis (De la Fuente Lopez et al., 2018; Olsen et al., 2017; Tanaka et al., 2016) and found that they were markedly upregulated in the EV‐HT29‐primed THP‐1 cells (68.7‐fold for IL‐6, 28.5‐fold for CCL1 and 40.2‐fold for CCL2), according to the gene microarray analysis (Figure 2d, Figure S3c).