BTG3 and systemic lupus erythematosus: Furthermore, multivariate analysis revealed that young age (< 40 years; OR, 6.307 [95% CI, 1.114–34.908]; P = 0.035), organ bleeding (OR, 13.672 [95% CI, 2.437–76.689]; P = 0.003), and ANA positivity (≥ 1:160) (OR, 6.638 [95% CI, 1.399–31.504]; P = 0.017) were significantly associated with an increased risk of the development of SLE in patients with ITP.