RUNX1 and acute myeloid leukemia: Subsequently, additional fusion genes caused by chromosomal translocations were identified, such as RUNX1-RUNX1T1 in AML with t(8;21)(q22;q22), CBFB-MYH11 in AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22), and PML-RARA in acute promyelocytic leukemia with t(15;17)(q22;q21).