Bridging integrator 3 (BIN3), cordon-bleu WH2 repeat protein like 1 (COBLL1), eukaryotic translation elongation factor 1 alpha lysine and N-terminal methyltransferase (EEF1AKNMT), long intergenic non-protein coding RNA 601 (LINC00601), sestrin 2 (SESN2), and Tumor necrosis factor receptor superfamily member 10a (TNFRSF10A) were differentially expressed comparing fibroblasts of both cancer groups to N0 after HDIR (model 1). This evidence concerns the gene METTL13 and cancer.