IRF1 and cancer: Results from pathway analysis were further supported by the corresponding molecular networks and their attributed functions and diseases, where N0 and N1 had DNA Repair as associated function, while only N2+ included Cancer. After LDIR, a key molecule among others (PGR, PCNA, TP53INP1 IL15, HSPA8, SOD1, CHUK, IRF1, CDC6, CCNE2) in the network of N0 was DDB2, with important functions for (excision-) repair and cell fate decision (Sugasawa et al. 2019; Stoyanova et al. 2009).