To study the long-term effect of HDAC6 inhibition by M-100 on B-cell lymphomagenesis, 70-day-old Eμ-Myc mice with a high incidence for lymphoma development [25], received i.p. injections with 30 mg/kg M-100 or vehicle every 72 h for six weeks. The gene discussed is HDAC6; the disease is lymphoma.