Advanced DKD samples showed increased expression of GR (NR3C1, fold-change = 1.16, padj = 0.02) and VCAM1 (fold-change = 1.36, padj = 0.006) and decreased expression of INSR (fold-change = 0.49, padj = 1.6 × 10−12), HSD11B2 (fold-change = 0.38, padj = 3.6 × 10−8) and FKBP5 (fold-change = 0.46, padj = 0.0009). The gene discussed is INSR; the disease is diabetic kidney disease.