GRM3 and Intellectual disability: We found eight genes to be associated with psychiatric and developmental diseases including: ELAVL4, EMX2, GRIA4, UNC13B, GABRG2, GRIK1, GRM3, KCNJ3, and KCNH5. Using tri whole-exome sequencing on GRIA4, Martin et al.53 had identified de novo pathogenic variants in unrelated individuals suffering from intellectual disabilities.