Twelve of the selected proteins were previously reported as relevant for thyroid cancers (Table 1), namely, alpha 2-HS glycoprotein (AHSG)23, annexin A1 (ANXA1)24, clusterin (CLU)25, galectin-3 (LGALS3)26, calreticulin (CALR)27, phosphatidylethanolamine-binding protein 1 (PEBP1)28, heat shock protein beta-1 (HSPB1)29, adenylate kinase isoenzyme 1 (AK1)30, signal transducer and activator of transcription 1-alpha/beta (STAT1)31, matrilin-2 (MATN2)32, DNA-dependent protein kinase catalytic subunit (PRKDC)33, and fibronectin (FN1)34. The gene discussed is AK1; the disease is thyroid cancer.