At baseline: i) Personal and demographic data; ii) Psoriasis duration and localization; iii) Presence of psoriatic arthritis (PsA) and duration; iv) Comorbidities; v) Previous systemic therapies; vi) Psoriasis severity using Psoriasis Area and Severity Index (PASI) and Body Surface Area (BSA); vii) Dermatology Life Quality of Index score (DLQI) in patients and caregivers; viii) Blood tests [blood count, transaminases, creatinine, azotemia, glycemia, erythrocyte sedimentation rate, C-reactive protein, cholesterol and triglyceride levels, protein electrophoresis] were recorded. The gene discussed is CRP; the disease is psoriasis.