An earlier report from the same group had shown that translation of AURKA mRNA is up-regulated downstream of EGF signalling in EGFR-overexpressed colorectal cancer, as pulse-chase assays confirmed increased de novo AURKA protein synthesis and AURKA mRNA was found more associated with the ribosomal S6 protein upon EGF treatment [11]. This evidence concerns the gene AURKA and colorectal cancer.