Furthermore, AURKA was found transcriptionally enhanced by Ewing sarcoma breakpoint region 1-Friend Leukaemia Integration 1 (EWS-Fli1) fusion protein, which results from a chromosomal translocation, in Ewing sarcoma cells following EWS-Fli1 binding to a Ets-binding site at −84 to −71 [34]. The gene discussed is FLI1; the disease is Ewing sarcoma.