As previously demonstrated for VCA [19] and gp350/220 [14], EBV infection stimulated the generation of p18-, gp350/220- and EBNA-1-specific IgG1 titers while p47/54-specific IgM failed to switch to a sustained IgG1 memory response (Fig 2B (overview), S2B Fig (detailed)). This evidence concerns the gene CD40LG and Epstein-Barr virus infection.