THY1 and systemic sclerosis: Remarkably, while there was almost no expression of Thy-1 in the reticular dermis from healthy control skin (9.3% ± 8.7%), Thy-1 was expressed in SSc with increasing levels over time in early-stage patients (disease duration < 3 years) demonstrating moderate expression (36.8% ± 11.1%) and later-stage patients showing high expression (69.2% ± 8.9%) (Figure 1, A–C).