To explore the therapeutic potential of BAF60c for AAA in vivo, an adenovirus carrying the human BAF60c gene (Ad-BAF60c, 2 × 109 viral particles/mouse) was delivered periadventitially to the suprarenal abdominal aorta of C57BL/6J mice after the Pcsk9/Ang II AAA model had been induced for 2 weeks (Supplemental Figure 4A). This evidence concerns the gene SMARCD3 and triple-A syndrome.