MAPT and tauopathy: Comparatively, in a sporadic FTLD-associated 3R tauopathy such as PiD, the most severe postmortem tau burden was observed in the medial temporal regions, i.e. the amygdala, the (para)hippocampus and the inferior temporal gyrus, along with the paralimbic anterior cingulate cortex, while the striatum is less affected [35].