Notably, a subset of P301L patients (cases 19, 24–26, 30–33) had mild to moderate globular tau inclusions in astrocytes and oligodendrocytes resembling sporadic globular glial tauopathy (GGT), and one patient with the IVS10 + 16 variant (case 36) had prominent white matter tau and astrocytic plaques that resembled sporadic corticobasal degeneration (CBD), while other IVS10 + 16 cases had more mixed glial tau morphologies (Table 2). This evidence concerns the gene MAPT and corticobasal degeneration disorder.