PNPLA3 and metabolic dysfunction-associated steatotic liver disease: Here, we studied three of the most widely validated NAFLD-associated common genetic variants, i.e., PNPLA3 (rs738409), TM6SF2 (rs58542926), and HSD17B13 (rs72613567) (Anstee et al., 2020; Liu et al., 2014; Luukkonen et al., 2017; Ma et al., 2019; Trepo and Valenti, 2020).