GRIA1 and Ataxia-telangiectasia: We found that there was a substantial reduction of mRNA expression of human GRIA1 (GSE61019: log2 fold-change of −0.35 ± 0.02, P < 0.01; unpaired Student’s t-test) in the cerebellum of patients with ataxia-telangiectasia (A-T), compared with the age-matched healthy individuals (Fig. 7a)56.