NAGLU and mucopolysaccharidosis type 3: Mucopolysaccharidosis type III (MPS III, Sanfilippo syndrome) includes four types, depending on the deficient enzyme: heparan N-sulphatase (type A, OMIM 252900), alpha-N-acetylglucosaminidase (type B, OMIM 252920), acetyl CoA:alpha-glucosaminide acetyltransferase (type C, OMIM 252930) and N-acetylglucosamine 6-sulphatase (type D, OMIM 252940).