For example, the editing level on two ubiquitination sites, chr1:110256304 on GSTM5 and chr4:10080600 on WDR1, were significantly different between tumor and para-tumor samples in Bladder Urothelial Carcinoma (BLCA) and Head and Neck squamous cell carcinoma (HNSC), respectively (Fig. 5A). This evidence concerns the gene GSTM5 and head and neck squamous cell carcinoma.