In these 27 patients, the primary tumor histological features were ER(−)/PR(−)/HER-2(+) in 21 patients (77.8%), ER(+)/PR(+)/HER-2(+) in 3 patients (11.1%), ER(−)/PR(−)/HER-2(−) in 1 patient (3.7%), ER(+)/PR(−)/HER-2(−) in 1 patient (3.7%), and ER(+)/PR(+)/HER-2(−) in 1 patient (3.7%). Here, ESR1 is linked to neoplasm.