IL10RB GReX was associated with increased incidence of COVID-19 related death in individuals of European descent (EUR; logistic regression; OR = 1.13; Bonferroni-adjusted p = 0.01; n = 14,262) and in the trans-ethnic meta-analysis (logistic regression; OR = 1.12; Bonferroni-adjusted p = 0.002; n = 23,226) (Fig. 3a and Supplementary Fig. 6); IFNAR2 GReX was not associated with COVID-19 death. Here, IFNAR2 is linked to COVID-19.