Binding sites between miR-885-3p and AURKA were also predicted through TargetScan database (Fig. 8H), which was validated by luciferase assay that after co-transfection with miR-885-3p-mimic, the luciferase activity in GC cells expressing AURKA 3’-UTR WT showed a significant decline compared to that in the control; however, co-transfection of AURKA 3′-UTR MUT and miR-885-3p-mimic didn’t change the luciferase activity of GC cells (Fig. 8I). Here, AURKA is linked to gastric cancer.