TRPM7 and gastric cancer: For gastric cancer, several studies suggest that TRPM7 participates in the survival of human gastric adenocarcinoma cells by acting as detoxifiers [28–30].Also, there are studies suggesting that TRPM7 expression is significantly higher in invasive breast ductal carcinomas compared with control subjects, and demonstrating that TRPM7 is involve in regulating breast cancer cell proliferation, apoptosis, EMT, migration, invasion and microcalcification [31, 32].