TRPM7 and cancer: Also shown in Table 2 and Figure S1, TRPM7 methylation remained negatively associated with lymph node metastasis (OR = 0.09; 95% CI = 0.03–0.27; P = 0.001) and cancer related death (OR = 0.20; 95% CI = 0.03–1.21; p = 0.07).