Increased expression of CHST11 mRNA was observed in bladder urothelial carcinoma, breast invasive carcinoma, cholangiocarcinoma, esophageal carcinoma, glioblastoma multiforme, head and neck squamous cell carcinoma, kidney renal clear cell carcinoma, kidney renal papillary cell carcinoma, liver hepatocellular carcinoma, stomach adenocarcinoma and Thyroid carcinoma (Figure 1A). The gene discussed is CHST11; the disease is head and neck squamous cell carcinoma.