ELISA measurement of IL-4 and IL-17 from BECs supernatant showed a higher concentration of IL-17 in severe asthma, much higher with severe asthma+E2 group, and the addition of DHT (severe asthma+ DHT) lowered the IL-17 concentration in severe asthma with statistical significance (Figure 4(b)). The gene discussed is IL4; the disease is asthma.