AKT1 and polycystic ovary syndrome: In the PCOS group, the expression levels of p-PI3K and p-AKT were significantly lower than those in the control group, while the protein levels of p-PI3K and p-AKT in the PCOS+CUR group were significantly higher than those in the PCOS group (Figures 4(a)–4(f)) (Supplemental Figure 2A).