In the last five years, a great number of research studies were focused on the study of growth arrest-specific transcript 5 (GAS5), a long noncoding RNA, which were found to play an important role as a tumor suppressor in many cancers, such as gastric cancer [21], ovarian cancer [22], cervical cancer[23], and esophageal squamous cell [24]. This evidence concerns the gene GAS5 and cancer.