In previous case series,[11, 12, 13, 14] following clinical, hormonal and radiological findings have been noted; Age of patients: 28-70 years, PPH: 99-100%, delay in diagnosis from PPH: around 1 -33 years, non-specific symptoms: 52%, agalactia: 74-94%, amenorrhoea: 33-82%, partial hypopituitarism: 45%, panhypopituitarism: 55%, lactotroph (Prolactin) and gonadotroph [Luteinizing hormone (LH), follicle stimulating hormone (FSH)] failure: 80-100%, corticotroph [Adrenocorticotrophic hormone (ACTH)] failure: 16-76%, thyrotroph [Thyroid stimulating hormone (TSH)] failure: 16-83%. Here, PLOD1 is linked to pulmonary arterial hypertension.