AKT1 and cerebral infarction: Xing et al. found that EA stimulation at the Quchi (LI11) and Zusanli (ST36) acupoints notably ameliorated neurological deficits and reduced the volume of cerebral infarction in MCAO rats while downregulating the expression level of Pten and upregulating the expression level of Akt, thereby it is speculated that EA exerted its protective effect through the Pten/Akt pathway (56).