Other targets in the treatment of glioblastoma are the inhibition of the notch signaling pathway that contributes to a decrease in glioblastoma cell proliferation and self-renewal (48, 49), the receptor for an epidermal growth factor (EGFR) (50), nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) (51). The gene discussed is EGF; the disease is glioblastoma.