The integrity of ELM and EZ on SD-OCT also reflects the level of VEGF in previous studies of macular edema secondary to diabetics (Saxena et al., 2017), central retinal vein occlusion (Wolf-Schnurrbusch et al., 2011), and myopic choroidal neovascularization (Ding et al., 2018). This evidence concerns the gene VEGFA and choroidal neovascularization.