Analysis of the HF indices N-terminal pro-brain natriuretic peptide (NT-proBNP), BNP and Galectin-3 also confirmed that serum levels of NT-proBNP, BNP and Galectin-3 in 3-month-old MYH6-Cre-BDNF–/– mice were significantly higher than those in WT mice (Figures 5IIa–c; p < 0.05). This evidence concerns the gene LGALS3 and hydrops fetalis.