ACTB and coronary artery disorder: The association was enhanced in male group with nine CpG sites exhibiting significantly higher methylation levels in CHD cases (ACTB_CpG_2.3, ACTB_CpG_7.8, ACTB_CpG_9.10, ACTB_CpG_12, and ACTB_CpG_15.16, ORs per +10% methylation ranging from 1.20 to 1.43, p < 0.030 for all by logistic regression model 2, Table 3B).