ACTB and hydrops fetalis: In addition, hypermethylation of seven CpG sites showed a borderline association with non-HF CHD cases (ACTB_CpG_2.3, ACTB_CpG_9.10, ACTB_CpG_12, and ACTB_CpG_15.16, ORs per +10% methylation ranging from 1.28 to 1.33, p < 0.034 for all by logistic regression model 2, Supplementary Table 8).