Several studies found that five mutations (MYH7-R403Q, MYH7-R453C, MYH7-G716R, MYH7-R719W, and TNNT2-R92W) were associated with a high incidence rate of SCD and, therefore, considered these mutations “high-risk” (13). The gene discussed is MYH7; the disease is Schnyder corneal dystrophy.