Genes exclusive of Community 3 are enriched in terms related to mitochondrial complex 1 NADH dehydrogenase, a finding in accordance with the typical association of Mitochondrial complex I deficiency with severe ID, encephalopathy, ataxia, and dystonia (Loeffen et al., 2000; Distelmaier et al., 2009; Pagniez-Mammeri et al., 2012; Valiente-Pallejà et al., 2018). Here, ENSG00000251605 is linked to hyperinsulinemic hypoglycemia, familial, 4.